Catalase, a heme enzyme present in peroxisomes, catalyzes the conversion of H2O2 to water and oxygen and oxidation of various compounds by H2O2.

Every week you are required to share 3 ideas, 2 examples/concepts, and 1 question/confusion from your the chapter readings. You will also need to respond and answer one of the questions/confusion posted by another student.

When posting the 3-2-1 please make sure you are not repeating 3-2-1 strategy of another student.

When sharing 3 ideas, students will need to include three topics/ideas they found intriguing. For the 2 concepts/examples, students will need to pick any two of the topics/ideas they posted and elaborate on then. Each topic you include 3-5 sentences to elaborate. For the 1 question you will need to include a question/unresolved issue for any concept. You will need to post your 3-2-1 by Thursday every week, so that the rest of the class has a chance to read and respond by 11:59 PM on Sunday each week.

For peer engagement, students will need to reply and answer one question from another student post. Students are encouraged to also read the 3-2-1 strategy from other students and include any other details they think might be interesting.

See an example below:

Week 1: Chapters 1, 2, and 8

3 ideas: 1. Role of lysosomes intracellular digestion of substances internalized by phagocytosis. 2. Peroxisomes have an important role in lipid metabolism. 3. DNA is more stable then RNA.

2 concepts (from the above 3 ideas, choose any two and explain in 3-5 sentences how it works?):

Peroxisomes have an important role in lipid metabolism: Peroxisomes are essential for oxidation of very long-chain fatty acids and synthesis of glycerolipids, glycerol ether lipids (plasmalogens), and isoprenoids.They also contain enzymes that oxidize D-amino acids, uric acid, and various 2-hydroxy acids using molecular O2 with formation of H2O2. Catalase, a heme enzyme present in peroxisomes, catalyzes the conversion of H2O2 to water and oxygen and oxidation of various compounds by H2O2.

DNA is more stable then RNA: DNA and RNA both have ribose sugar. RNA on the 2nd and 3rd carbon have hydorxyl group (-OH) which is reactive. In DNA only the 3rd carbon has the functional group which makes DNA less reactive and more stable.

1 question/confusion: In chapter 2, I am finding it hard to understand how topoisomerases work?

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