find the following article…
Bradbury, D., Simmons, T., Slater, K., & Crouch, S. (2000). Measurement of the ADP:ATP ratio in human leukaemic cell lines can be used as an indicator of cell viability, necrosis and apoptosis. Journal of Immunological Methods, 240(1-2), 79-92.
Use the article to answer the following questions:
1. What is the value/range of [ADP]/[ATP] in a cell undergoing apoptosis?
2. What is the value/range of [ADP]/[ATP] in a healthy cell?
3. When is the value/range of [ADP]/[ATP] > 15?
4. What is the role of mitochondria?
5. How is this group using the [ADP]/[ATP] ratio for their experiments?
6. How are they measuring [ADP]/[ATP]? Why might this be difficult?
7. Suggest another (can be totally unrelated) experiment that utilizes [ADP]/[ATP] values
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