Write a research article explaining the distinction between multiple sequence alignment and BLAST.Research tasks for this unit (due March 6, 2024)
Important Instructions:
• Your narrative has to reflect your understanding of the described algorithms.
• Your description of each algorithm has to give a reader a good idea about the goal
of the algorithm and how the algorithm works. For example, all steps of the
algorithm have to be clearly identified, and what is done at each of them described.
• Make sure that you follow all report requirements as specified in Syllabus
(including the rules on quotations, citations, and plagiarism).
• Page limit: max 12 pages (plus references).
Task 1: Pairwise sequence alignment:
Select one of the following algorithms and provide its detailed description, including
parameters, scoring, statistical significance of alignments, and examples of the
algorithm software implementations:
The Needleman-Wunsch Algorithm
The Smith-Waterman Algorithm
BLAST
PSI-BLAST
Page 6 of 6
Task 2: Multiple sequence alignment:
Select one of the following algorithms and provide its detailed description,
including parameters, scoring, statistical significance of alignments, and examples
of the algorithm software implementations.
• ClustalW / Clustal Omega
• T-Coffee
• MUSCLE
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